Start with structure
Write meaningful HTML first and then add Tailwind utilities. Semantic HTML remains important because Tailwind is a styling tool, not a replacement for accessible markup.
Build from outside to inside
A practical approach is to style the page container, then the section layout, then each component, and finally typography and interactive states. This makes complex utility strings easier to reason about.
Use readable formatting
Long class attributes can be formatted across lines in component templates when your framework and formatter support it. The goal is maintainability, not making every class appear on one line.